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Voriconazole (UK-109,496) inhibits the growth and alters the morphology of fluconazole-susceptible and -resistant Candida species.

The effects of voriconazole on the growth, ultrastructure, and leakage of cytoplasmic materials of Candida species were investigated. MIC data showed that voriconazole was more active than fluconazole. Exposure of yeast to voriconazole caused growth inhibition, cell wall thinning, and cell membrane...

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Main Authors: Belanger, P, Nast, C C, Fratti, R, Sanati, H, Ghannoum, M
格式: Artigo
語言:Inglês
出版: 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC164020/
https://ncbi.nlm.nih.gov/pubmed/9257776
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