Pharmacokinetics of L-749,345, a long-acting carbapenem antibiotic, in primates.

L-749,345 is a carbapenem antibiotic, currently in phase II clinical trials, which possesses a broad antibacterial spectrum and extended half-life. The time courses of levels of the drugs in plasma and urinary recovery were evaluated for L-749,345, imipenem-cilastatin (IPM), and ceftriaxone (CTX) in...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Sundelof, J G, Hajdu, R, Gill, C J, Thompson, R, Rosen, H, Kropp, H
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1997
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163997/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9257753/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.8.1743
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