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Small, anionic, and charge-neutralizing propeptide fragments of zymogens are antimicrobial.

Some inactive precursor proteins, or zymogens, contain small, amino terminus, homopolymeric regions of Asp that neutralize the cationic charge of the active protein during synthesis. After posttranslational cleavage, the anionic propeptide fragment may exhibit antimicrobial activity. To demonstrate...

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Bibliografski detalji
Glavni autori: Brogden, K A, Ackermann, M, Huttner, K M
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC163973/
https://ncbi.nlm.nih.gov/pubmed/9210699
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