In vivo selection of Klebsiella pneumoniae strains with enhanced quinolone resistance during fluoroquinolone treatment of urinary tract infections.

We report two cases of failure of fluoroquinolone treatment of urinary tract infections with Klebsiella pneumoniae strains harboring quinolone resistance-associated alterations in GyrA and ParC and in vivo selection of posttreatment isolates with enhanced fluoroquinolone resistance. Active efflux le...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Deguchi, T, Kawamura, T, Yasuda, M, Nakano, M, Fukuda, H, Kato, H, Kato, N, Okano, Y, Kawada, Y
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9210697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.7.1609
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