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Effect of severity of meningitis on fungicidal activity of flucytosine combined with fluconazole in a murine model of cryptococcal meningitis.

We studied the effect of the severity of meningitis on the response to therapy with fluconazole and flucytosine in a murine model of cryptococcal meningitis. Meningitis was established by intracerebral injection of Cryptococcus neoformans. The severity of meningitis was varied by delaying the onset...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Ding, J C, Bauer, M, Diamond, D M, Leal, M A, Johnson, D, Williams, B K, Thomas, A M, Najvar, L, Graybill, J R, Larsen, R A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163965/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9210691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.7.1589
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