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Metabolism of a 5-nitroimidazole in susceptible and resistant isogenic strains of Bacteroides fragilis.

We investigated the metabolism of dimetridazole (1,2-dimethyl-5-nitroimidazole) (DMZ) by the resting cell method in a susceptible strain of Bacteroides fragilis and in the same strain containing the nimA gene, which conferred resistance to 5-nitroimidazole drugs. In both cases, under strict anaerobi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Carlier, J P, Sellier, N, Rager, M N, Reysset, G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163946/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9210672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.7.1495
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