Učitavanje...
Characterization of a mutation in the parE gene that confers fluoroquinolone resistance in Streptococcus pneumoniae.
We report a mutation in the parE genes of two in vitro mutants of Streptococcus pneumoniae responsible for low-level resistance to fluoroquinolones. Sequential acquisition of mutations in parE and gyrA leads to higher levels of resistance. This confirms that topoisomerase IV is the primary target of...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1997
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC163872/ https://ncbi.nlm.nih.gov/pubmed/9145891 |
| Oznake: |
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