Pharmacodynamic modeling of the in vivo interaction between cefotaxime and ofloxacin by using serum ultrafiltrate inhibitory titers.

The pharmacokinetics (PK) and pharmacodynamics (PD) of cefotaxime and ofloxacin and of their combination were examined in a three-period randomized crossover study involving 12 healthy adults. The PK of cefotaxime and ofloxacin were modeled. PD was assessed from the predicted concentrations in serum...

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Detaylı Bibliyografya
Asıl Yazarlar: Nix, D E, Wilton, J H, Hyatt, J, Thomas, J, Strenkoski-Nix, L C, Forrest, A, Schentag, J J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC163858/
https://ncbi.nlm.nih.gov/pubmed/9145877
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