Efficacy of trimethoprim in murine experimental infection with a thymidine kinase-deficient mutant of Escherichia coli.
The antimicrobial activity of trimethoprim is antagonized by thymidine in in vitro susceptibility tests. The purpose of this investigation was to determine whether this antagonism also occurred during experimental infection in mice, which have high serum thymidine concentrations. We derived a mutant...
محفوظ في:
| الحاوية / القاعدة: | Antimicrob Agents Chemother |
|---|---|
| المؤلفون الرئيسيون: | , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
1997
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163847/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9145866/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.5.1042 |
| الوسوم: |
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