Modulation of the metabolism of beta-L-(-)-2',3'-dideoxy-3'-thiacytidine by thymidine, fludarabine, and nitrobenzylthioinosine.

beta-L-(-)-2',3'-Dideoxy-3'-thiacytidine (3TC) is a cytosine nucleoside analog that potently inhibits the replication of human and duck hepatitis B viruses and human immunodeficiency virus through the activity of its 5'-triphosphate ester metabolite. The present study examined the intracellular deca...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Rahn, J J, Kieller, D M, Tyrrell, D L, Gati, W P
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1997
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9145844/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.5.918
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