Human immunodeficiency virus type 1 reverse transcriptase genotype and drug susceptibility changes in infected individuals receiving dideoxyinosine monotherapy for 1 to 2 years.

The genetic mechanisms of human immunodeficiency virus type 1 (HIV-1) resistance to dideoxyinosine (ddI) in vivo have been described based on data from primary HIV-1 isolates. To better define the spectrum of HIV-1 reverse transcriptase (RT) changes occurring during ddI therapy, we determined the ge...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Winters, M A, Shafer, R W, Jellinger, R A, Mamtora, G, Gingeras, T, Merigan, T C
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9087484/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.4.757
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