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The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2

Numerous bacteria cope with the scarcity of iron in their microenvironment by synthesizing small iron-scavenging molecules known as siderophores. Mammals have evolved countermeasures to block siderophore-mediated iron acquisition as part of their innate immune response. Secreted lipocalin 2 (Lcn2) s...

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Detalhes bibliográficos
Main Authors: Fischbach, Michael A., Lin, Hening, Zhou, Lu, Yu, Yang, Abergel, Rebecca J., Liu, David R., Raymond, Kenneth N., Wanner, Barry L., Strong, Roland K., Walsh, Christopher T., Aderem, Alan, Smith, Kelly D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637611/
https://ncbi.nlm.nih.gov/pubmed/17060628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604636103
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