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Ubiquitin-associated domain of Mex67 synchronizes recruitment of the mRNA export machinery with transcription

The mRNA nuclear export receptor Mex67/Mtr2 is recruited to mRNAs through RNA-binding adaptors, including components of the THO/TREX complex that couple transcription to mRNA export. Here we show that the ubiquitin-associated (UBA) domain of Mex67 is not only required for proper nuclear export of mR...

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Autori principali: Gwizdek, Carole, Iglesias, Nahid, Rodriguez, Manuel S., Ossareh-Nazari, Batool, Hobeika, Maria, Divita, Gilles, Stutz, Françoise, Dargemont, Catherine
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637590/
https://ncbi.nlm.nih.gov/pubmed/17056718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607941103
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