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Ancient polymorphism and functional variation in the primate MHC-DQA1 5′ cis-regulatory region
Precise regulation of MHC gene expression is critical to vertebrate immune surveillance and response. Polymorphisms in the 5′ proximal promoter region of the human class II gene HLA-DQA1 have been shown to influence its transcriptional regulation and may contribute to the pathogenesis of autoimmune...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1637582/ https://ncbi.nlm.nih.gov/pubmed/17053068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607662103 |
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