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Monitoring intermediate filament assembly by small-angle x-ray scattering reveals the molecular architecture of assembly intermediates

Intermediate filaments (IFs), along with microtubules, microfilaments, and associated cross-bridging proteins, constitute the cytoskeleton of metazoan cells. While crystallographic data on the dimer representing the elementary IF “building block” have recently become available, little structural det...

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Main Authors: Sokolova, Anna V., Kreplak, Laurent, Wedig, Tatjana, Mücke, Norbert, Svergun, Dmitri I., Herrmann, Harald, Aebi, Ueli, Strelkov, Sergei V.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637561/
https://ncbi.nlm.nih.gov/pubmed/17050693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603629103
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