A 500-bp region, ≈40 kb upstream of the human CYP19 (aromatase) gene, mediates placenta-specific expression in transgenic mice

In humans, aromatase P450 (product of CYP19 gene), which catalyzes conversion of C(19) steroids to estrogens, is expressed in a number of tissues, including ovary, adipose, and syncytiotrophoblast of the placenta. The 5′ untranslated regions of CYP19 mRNA transcripts in these tissues are encoded by...

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Detaylı Bibliyografya
Asıl Yazarlar: Kamat, Amrita, Graves, Katherine H., Smith, Margaret E., Richardson, James A., Mendelson, Carole R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1999
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC16374/
https://ncbi.nlm.nih.gov/pubmed/10200304
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