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Relationships between antimicrobial effect and area under the concentration-time curve as a basis for comparison of modes of antibiotic administration: meropenem bolus injections versus continuous infusions.
In comparative studies of different modes of administration (MAs) simulated in in vitro dynamic models, only one dose of antibiotic is usually mimicked. Such an experimental design can provide a prediction of the antimicrobial effect (AME) of a given combination of drug, clinical isolate, and infect...
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Hoofdauteurs: | , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
1997
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC163713/ https://ncbi.nlm.nih.gov/pubmed/9021191 |
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