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SRR-SB3, a disulfide-containing macrolide that inhibits a late stage of the replicative cycle of human immunodeficiency virus.

From a series of macrocyclic diamides possessing the disulfide linkage, only SRR-SB3, a compound that complexes with zinc, was found to inhibit human immunodeficiency virus type 1 (HIV-1; strain IIIB) replication at a concentration of 1.8 to 6.5 micrograms/ml in MT-4, CEM, and peripheral blood monon...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Witvrouw, M, Balzarini, J, Pannecouque, C, Jhaumeer-Laulloo, S, Esté, J A, Schols, D, Cherepanov, P, Schmit, J C, Debyser, Z, Vandamme, A M, Desmyter, J, Ramadas, S R, de Clercq, E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163699/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9021177/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.2.262
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