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Differentiation-Induced Cleavage of Cutl1/CDP Generates a Novel Dominant-Negative Isoform That Regulates Mammary Gene Expression

Cutl1/CCAAT displacement protein (CDP) is a transcriptional repressor of mouse mammary tumor virus (MMTV), a betaretrovirus that is a paradigm for mammary-specific gene regulation. Virgin mammary glands have high levels of full-length CDP (200 kDa) that binds to negative regulatory elements (NREs) t...

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Detalhes bibliográficos
Main Authors: Maitra, Urmila, Seo, Jin, Lozano, Mary M., Dudley, Jaquelin P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636867/
https://ncbi.nlm.nih.gov/pubmed/17015474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01083-06
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