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Induction of Gene Silencing by Hairpin RNA Expression in Tetrahymena thermophila Reveals a Second Small RNA Pathway

Unlike in other eukaryotes, in which it causes gene silencing, RNA interference (RNAi) has been linked to programmed DNA deletion in the ciliate Tetrahymena thermophila. Here we have developed an efficient method to inducibly express double-stranded RNA hairpins and demonstrated that they cause gene...

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Detalhes bibliográficos
Main Authors: Howard-Till, Rachel A., Yao, Meng-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636817/
https://ncbi.nlm.nih.gov/pubmed/17000759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01430-06
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