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Specific Differentially Methylated Domain Sequences Direct the Maintenance of Methylation at Imprinted Genes

Landmark features of imprinted genes are differentially methylated domains (DMDs), in which one parental allele is methylated on CpG dinucleotides and the opposite allele is unmethylated. Genetic experiments in the mouse have shown that DMDs are required for the parent-specific expression of linked...

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Autors principals: Reinhart, Bonnie, Paoloni-Giacobino, Ariane, Chaillet, J. Richard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636798/
https://ncbi.nlm.nih.gov/pubmed/16954379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00981-06
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