Synergism between tobramycin and ceftazidime against a resistant Pseudomonas aeruginosa strain, tested in an in vitro pharmacokinetic model.

Synergism between two antibiotics is usually tested by a checkerboard titration technique, or by time-kill methods. Both methods have the disadvantage that synergism is determined at constant concentrations of the antibiotics, which do not reflect reality in vivo. In the present study we determined...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	den Hollander, J G, Horrevorts, A M, van Goor, M L, Verbrugh, H A, Mouton, J W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8980762/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.1.95
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