MUC1 gene overexpressed in breast cancer: structure and transcriptional activity of the MUC1 promoter and role of estrogen receptor alpha (ERα) in regulation of the MUC1 gene expression

BACKGROUND: The MUC1 gene encodes a mucin glycoprotein(s) which is basally expressed in most epithelial cells. In breast adenocarcinoma and a variety of epithelial tumors its transcription is dramatically upregulated. Of particular relevance to breast cancer, steroid hormones also stimulate the expr...

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Detalhes bibliográficos
Main Authors: Zaretsky, Joseph Z, Barnea, Itay, Aylon, Yael, Gorivodsky, Marat, Wreschner, Daniel H, Keydar, Iafa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636664/
https://ncbi.nlm.nih.gov/pubmed/17083744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-5-57
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