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Regulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteins

In mammalian cells, DNA methylation is associated with heritable and stable gene repression, mediated in part by methyl-CpG-binding domain (MBD) proteins that recruit corepressors to modify chromatin. MBD1 protein, a member of the MBD family, forms a complex with SETDB1 histone methylase to silence...

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Detalhes bibliográficos
Main Authors: Lyst, Matthew J, Nan, Xinsheng, Stancheva, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636622/
https://ncbi.nlm.nih.gov/pubmed/17066076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601404
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