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Regulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteins
In mammalian cells, DNA methylation is associated with heritable and stable gene repression, mediated in part by methyl-CpG-binding domain (MBD) proteins that recruit corepressors to modify chromatin. MBD1 protein, a member of the MBD family, forms a complex with SETDB1 histone methylase to silence...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636622/ https://ncbi.nlm.nih.gov/pubmed/17066076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601404 |
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