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Disulfide cross-linking indicates that FlgM-bound and free σ(28) adopt similar conformations
The dissociable σ subunit of bacterial RNA polymerase is required for the promoter-specific initiation of transcription. When bound to RNA polymerase, σ makes sequence-specific promoter contacts and plays a crucial role in DNA melting. In isolation, however, σ lacks significant promoter binding acti...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636522/ https://ncbi.nlm.nih.gov/pubmed/17075066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606482103 |
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