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Disulfide cross-linking indicates that FlgM-bound and free σ(28) adopt similar conformations

The dissociable σ subunit of bacterial RNA polymerase is required for the promoter-specific initiation of transcription. When bound to RNA polymerase, σ makes sequence-specific promoter contacts and plays a crucial role in DNA melting. In isolation, however, σ lacks significant promoter binding acti...

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Hlavní autoři: Sorenson, Margareta K., Darst, Seth A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636522/
https://ncbi.nlm.nih.gov/pubmed/17075066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606482103
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