Evolutionarily conserved and non-conserved retrovirus restriction activities of artiodactyl APOBEC3F proteins

The APOBEC3 proteins are unique to mammals. Many inhibit retrovirus infection through a cDNA cytosine deamination mechanism. HIV-1 neutralizes this host defense through Vif, which triggers APOBEC3 ubiquitination and degradation. Here, we report an APOBEC3F-like, double deaminase domain protein from...

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Bibliographic Details
Main Authors: Jónsson, Stefán R., Haché, Guylaine, Stenglein, Mark D., Fahrenkrug, Scott C., Andrésdóttir, Valgerdur, Harris, Reuben S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2006
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636497/
https://ncbi.nlm.nih.gov/pubmed/17038330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl721
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