Sirolimus pharmacokinetics in pediatric renal transplant recipients receiving calcineurin inhibitor co-therapy

We have previously reported sirolimus (SRL) pharmacokinetics (PK) in pediatric renal transplant recipients on a calcineurin inhibitor (CNI)-free protocol. We now report pediatric SRL PK in pediatric renal transplant patients receiving SRL + CNI. SRL was dosed to achieve target trough levels between...

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Autori principali: Schachter, Asher D., Benfield, Mark R., Wyatt, Robert J., Grimm, Paul C., Fennell, Robert S., Herrin, John T., Lirenman, David S., McDonald, Ruth A., Munoz-Arizpe, Ricardo, Harmon, William E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636453/
https://ncbi.nlm.nih.gov/pubmed/17096757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-3046.2006.00541.x
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