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Utilising the left-helical conformation of L-DNA for analysing different marker types on a single universal microarray platform

L-DNA is the perfect mirror-image form of the naturally occurring d-conformation of DNA. Therefore, L-DNA duplexes have the same physical characteristics in terms of solubility, duplex stability and selectivity as D-DNA but form a left-helical double-helix. Because of its chiral difference, L-DNA do...

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Autori principali: Hauser, Nicole C., Martinez, Rafael, Jacob, Anette, Rupp, Steffen, Hoheisel, Jörg D., Matysiak, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636439/
https://ncbi.nlm.nih.gov/pubmed/16990248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl671
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