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Multiple efflux mechanisms are involved in Candida albicans fluconazole resistance.

Fluconazole-susceptible Candida albicans strains accumulated [3H]fluconazole at a rate of approximately 2 pmol/min per 10(9) cells. Fluconazole accumulation was not affected by the pretreatment of cells with sodium azide or with 2-deoxyglucose. The rate of fluconazole accumulation became saturated a...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphov: Albertson, G D, Niimi, M, Cannon, R D, Jenkinson, H F
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 1996
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163632/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9124851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.12.2835
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