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Naturally azole-resistant Leishmania braziliensis promastigotes are rendered susceptible in the presence of terbinafine: comparative study with azole-susceptible Leishmania mexicana promastigotes.

Leishmania braziliensis (isolate 2903) was naturally resistant to ketoconazole or the bis-triazole D0870, inhibitors of sterol C-14 demethylase, which produced only moderate effects on the proliferation of promastigotes at 10 microM. In contrast, Leishmania mexicana (isolate NR) was extremely suscep...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Rangel, H, Dagger, F, Hernandez, A, Liendo, A, Urbina, J A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163622/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9124841/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.12.2785
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