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Cryptosporidium parvum metalloaminopeptidase inhibitors prevent in vitro excystation.

Cryptosporidium parvum arginine aminopeptidase (RAP) was studied during in vitro excystation. Specific RAP inhibitors were identified by using C. parvum extracts. Amastatin, a series of alpha-aminoboronic acids, and the chelating agents EDTA and 1,10-phenanthrolene, but not endoproteinase inhibitors...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Okhuysen, P C, Chappell, C L, Kettner, C, Sterling, C R
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1996
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163621/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9124840/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.12.2781
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