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Characterization of peripheral-compartment kinetics of antibiotics by in vivo microdialysis in humans.

The calculation of pharmacokinetic/pharmacodynamic surrogates from concentrations in serum has been shown to yield important information for the evaluation of antibiotic regimens. Calculations based on concentrations in serum, however, may not necessarily be appropriate for peripheral-compartment in...

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Autors principals: Müller, M, Haag, O, Burgdorff, T, Georgopoulos, A, Weninger, W, Jansen, B, Stanek, G, Pehamberger, H, Agneter, E, Eichler, H G
Format: Artigo
Idioma:Inglês
Publicat: 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC163607/
https://ncbi.nlm.nih.gov/pubmed/9124826
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