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Development of experimental pneumonia by infection with penicillin-insensitive Streptococcus pneumoniae in guinea pigs and their treatment with amoxicillin, cefotaxime, and meropenem.

Acute respiratory infection with penicillin-insensitive Streptococcus pneumoniae (MIC and MBC, 1 and 2 micrograms/ml, respectively) was established in guinea pigs. Intratracheal instillation of 0.5 ml of an overnight culture of S. pneumoniae concentrated 25 times (approximately 3 x 10(9) CFU) induce...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Ponte, C, Parra, A, Nieto, E, Soriano, F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163606/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9124825/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.12.2698
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