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Suppression of methicillin resistance in a mecA-containing pre-methicillin-resistant Staphylococcus aureus strain is caused by the mecI-mediated repression of PBP 2' production.

The mechanism of methicillin susceptibility was studied in Staphylococcus aureus N315P, a pre-methicillin-resistant S. aureus strain that is susceptible to methicillin, despite the presence of mecA in the chromosome. In the presence of mec regulator genes mecI and mecR1, transcription of the mecA ge...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Kuwahara-Arai, K, Kondo, N, Hori, S, Tateda-Suzuki, E, Hiramatsu, K
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1996
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163603/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9124822/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.12.2680
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