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IgD, like IgM, is a primordial immunoglobulin class perpetuated in most jawed vertebrates

IgD has remained a mysterious Ig class and a bane to immunology students since its discovery >40 years ago. Its spotty occurrence in mammals and birds and the discovery of an isotype with similarities to IgD in bony fish are perplexing. We have identified IgD heavy (H) chain (δ) from the amphibia...

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Bibliografiske detaljer
Main Authors: Ohta, Yuko, Flajnik, Martin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636022/
https://ncbi.nlm.nih.gov/pubmed/16818885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601407103
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