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The hop phytoestrogen, 8-prenylnaringenin, reverses the ovariectomy-induced rise in skin temperature in an animal model of menopausal hot flushes.

The mechanisms underlying menopausal hot flushes are poorly understood, although it is generally assumed they result from disturbances of thermoregulatory centres in the hypothalamus. 8-prenylnaringenin (8-PN) has been identified as a potent phytoestrogen in hops (Humulus lupulus) and there are clai...

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Autori principali: Bowe, James, Li, Xiao Feng, Kinsey-Jones, James, Heyerick, Arne, Brain, Susan, Milligan, Stuart, O'Byrne, Kevin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635969/
https://ncbi.nlm.nih.gov/pubmed/17088409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/joe.1.06919
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