Calcium Channel α(2)δ(1) Subunit Mediates Spinal Hyperexcitability in Pain Modulation

Mechanisms of chronic pain, including neuropathic pain, are poorly understood. Upregulation of voltage-gated calcium channel (VGCC) α(2)δ(1) subunit (Ca(v)α(2)δ(1)) in sensory neurons and dorsal spinal cord by peripheral nerve injury has been suggested to contribute to neuropathic pain. To investiga...

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Autori principali: Li, Chun-Ying, Zhang, Xiu-Lin, Matthews, Elizabeth A., Li, Kang-Wu, Kurwa, Ambereen, Boroujerdi, Amin, Gross, Jimmy, Gold, Michael S., Dickenson, Anthony H., Feng, Guoping, Luo, Z. David
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635965/
https://ncbi.nlm.nih.gov/pubmed/16764990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2006.04.022
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