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Recognition of aminoglycoside antibiotics by enterococcal-staphylococcal aminoglycoside 3'-phosphotransferase type IIIa: role of substrate amino groups.

The interactions of the aminoglycoside 3'-phosphotransferase IIIa with aminoglycoside antibiotics lacking specific amino groups were examined by steady-state kinetic analyses. The results demonstrate that an amino group on C-1 and either an amino or a hydroxyl group at the 2' and 6' positions are im...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Principais autores: McKay, G A, Roestamadji, J, Mobashery, S, Wright, G D
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 1996
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163593/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8913482/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.11.2648
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