N-1-tert-butyl-substituted quinolones: in vitro anti-Mycobacterium avium activities and structure-activity relationship studies.

We determined the MICs of 63 quinolones against 14 selected reference and clinical strains of the Mycobacterium avium-Mycobacterium intracellulare complex. Sixty-one of the compounds were selected from the quinolone library at Parke-Davis, Ann Arbor, Mich., including N-1-tert-butyl-substituted agent...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Klopman, G, Fercu, D, Renau, T E, Jacobs, M R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163590/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8913479/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.11.2637
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