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In vivo activities of ceftriaxone and vancomycin against Borrelia spp. in the mouse brain and other sites.

Borrelia burgdorferi, the agent of Lyme disease, and B. turicatae, a neurotropic agent of relapsing fever, are susceptible to vancomycin in vitro, with an MIC of 0.5 microgram/ml. To determine the activity of vancomycin in vivo, particularly in the brain, we infected adult immunocompetent BALB/c and...

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Published in:Antimicrob Agents Chemother
Main Authors: Kazragis, R J, Dever, L L, Jorgensen, J H, Barbour, A G
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163589/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8913478/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.11.2632
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