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Pathway-specific differences between tumor cell lines and normal and tumor tissue cells

BACKGROUND: Cell lines are used in experimental investigation of cancer but their capacity to represent tumor cells has yet to be quantified. The aim of the study was to identify significant alterations in pathway usage in cell lines in comparison with normal and tumor tissue. METHODS: This study ut...

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Main Authors: Ertel, Adam, Verghese, Arun, Byers, Stephen W, Ochs, Michael, Tozeren, Aydin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635729/
https://ncbi.nlm.nih.gov/pubmed/17081305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-5-55
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