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Large Conformational Changes in a Kinesin Motor Catalyzed by Interaction with Microtubules

Kinesin motor proteins release nucleotide upon interaction with microtubules (MTs), then bind and hydrolyze ATP to move along the MT. Although crystal structures of kinesin motors bound to nucleotides have been solved, nucleotide-free structures have not. Here, using cryomicroscopy and three-dimensi...

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Bibliografske podrobnosti
Main Authors: Hirose, Keiko, Akimaru, Erika, Akiba, Toshihiko, Endow, Sharyn A., Amos, Linda A.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635653/
https://ncbi.nlm.nih.gov/pubmed/16973442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.07.020
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