Dendritic cell-mediated HIV-1 transmission to T cells of LAD-1 patients is impaired due to the defect in LFA-1

BACKGROUND: Dendritic cells (DC) have been proposed to mediate sexual HIV-1 transmission by capturing the virus in the mucosa and subsequently presenting it to CD4(+ )T cells. We have demonstrated before that DC subsets expressing higher levels of intercellular adhesion molecule-1 (ICAM-1) are bette...

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Detalhes bibliográficos
Main Authors: Groot, Fedde, Kuijpers, Taco W, Berkhout, Ben, de Jong, Esther C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635562/
https://ncbi.nlm.nih.gov/pubmed/17078873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-3-75
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