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Kaposi sarcoma herpesvirus K5 removes CD31/PECAM from endothelial cells

The transmembrane ubiquitin ligase K5/MIR2 of Kaposi sarcoma herpesvirus (KSHV) mediates internalization and lysosomal degradation of glycoproteins involved in antigen presentation and co-stimulation. In endothelial cells (ECs), K5 additionally reduced expression of CD31/platelet–endothelial cell ad...

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Autori principali: Mansouri, Mandana, Douglas, Janet, Rose, Patrick P., Gouveia, Kristine, Thomas, Gary, Means, Robert E., Moses, Ashlee V., Früh, Klaus
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Hematology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635550/
https://ncbi.nlm.nih.gov/pubmed/16601245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-11-4404
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