Direct Inhibition of T-Cell Responses by the Cryptococcus Capsular Polysaccharide Glucuronoxylomannan

The major virulence factor of the pathogenic fungi Cryptococcus neoformans and C. gattii is the capsule. Glucuronoxylomannan (GXM), the major component of the capsule, is a high-molecular-weight polysaccharide that is shed during cryptococcosis and can persist in patients after successful antifungal...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Yauch, Lauren E, Lam, Jennifer S, Levitz, Stuart M
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2006
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635532/
https://ncbi.nlm.nih.gov/pubmed/17096589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0020120
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