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Prenatal and postpartum pharmacokinetics of stavudine (2',3'-didehydro-3'-deoxythymidine) and didanosine (dideoxyinosine) in pigtailed macaques (Macaca nemestrina).

Stavudine (5 mg/kg of body weight; n = 7) or didanosine (3.2 mg/kg; n = 4) was administered as an intravenous bolus to pregnant pigtailed macaques (Macaca nemestrina) near term and 4 to 5 weeks postpartum. No significant differences were found between the prenatal and postpartum total plasma drug cl...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Odinecs, A, Pereira, C, Nosbisch, C, Unadkat, J D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163547/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8891157/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.10.2423
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