A Single Common Portal for Clathrin-mediated Endocytosis of Distinct Cargo Governed by Cargo-selective Adaptors

Sorting of transmembrane cargo into clathrin-coated vesicles requires endocytic adaptors, yet RNA interference (RNAi)-mediated gene silencing of the AP-2 adaptor complex only disrupts internalization of a subset of clathrin-dependent cargo. This suggests alternate clathrin-associated sorting protein...

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Autores principales: Keyel, Peter A., Mishra, Sanjay K., Roth, Robyn, Heuser, John E., Watkins, Simon C., Traub, Linton M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2006
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635374/
https://ncbi.nlm.nih.gov/pubmed/16870701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-05-0421
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