PIAS3 induction of PRB sumoylation represses PRB transactivation by destabilizing its retention in the nucleus

Progesterone receptor (PR) plays a critical role in cell proliferation and differentiation, and its transcriptional activity is known to be modulated by cofactor proteins. In the present study, we demonstrated that in the presence of progesterone, protein inhibitor of activated STAT-3 (PIAS3) signif...

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Detalhes bibliográficos
Main Authors: Man, Jiang-Hong, Li, Hui-Yan, Zhang, Pei-Jing, Zhou, Tao, He, Kun, Pan, Xin, Liang, Bing, Li, Ai-Ling, Zhao, Jie, Gong, Wei-Li, Jin, Bao-Feng, Xia, Qing, Yu, Ming, Shen, Bei-Fen, Zhang, Xue-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635300/
https://ncbi.nlm.nih.gov/pubmed/17020914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl691
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