PIAS3 induction of PRB sumoylation represses PRB transactivation by destabilizing its retention in the nucleus

Progesterone receptor (PR) plays a critical role in cell proliferation and differentiation, and its transcriptional activity is known to be modulated by cofactor proteins. In the present study, we demonstrated that in the presence of progesterone, protein inhibitor of activated STAT-3 (PIAS3) signif...

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Dettagli Bibliografici
Autori principali: Man, Jiang-Hong, Li, Hui-Yan, Zhang, Pei-Jing, Zhou, Tao, He, Kun, Pan, Xin, Liang, Bing, Li, Ai-Ling, Zhao, Jie, Gong, Wei-Li, Jin, Bao-Feng, Xia, Qing, Yu, Ming, Shen, Bei-Fen, Zhang, Xue-Min
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2006
Soggetti:
Molecular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635300/
https://ncbi.nlm.nih.gov/pubmed/17020914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl691
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