The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II

CDK8 (cyclin-dependent kinase 8), along with CycC, Med12, and Med13, form a repressive module (the Cdk8 module) that prevents RNA polymerase II (pol II) interactions with Mediator. Here, we report that the ability of the Cdk8 module to prevent pol II interactions is independent of the Cdk8-dependent...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Elmlund, Hans, Baraznenok, Vera, Lindahl, Martin, Samuelsen, Camilla O., Koeck, Philip J. B., Holmberg, Steen, Hebert, Hans, Gustafsson, Claes M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2006
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635081/
https://ncbi.nlm.nih.gov/pubmed/17043218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607483103
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