The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II

CDK8 (cyclin-dependent kinase 8), along with CycC, Med12, and Med13, form a repressive module (the Cdk8 module) that prevents RNA polymerase II (pol II) interactions with Mediator. Here, we report that the ability of the Cdk8 module to prevent pol II interactions is independent of the Cdk8-dependent...

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Detalles Bibliográficos
Main Authors: Elmlund, Hans, Baraznenok, Vera, Lindahl, Martin, Samuelsen, Camilla O., Koeck, Philip J. B., Holmberg, Steen, Hebert, Hans, Gustafsson, Claes M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635081/
https://ncbi.nlm.nih.gov/pubmed/17043218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607483103
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