The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II

CDK8 (cyclin-dependent kinase 8), along with CycC, Med12, and Med13, form a repressive module (the Cdk8 module) that prevents RNA polymerase II (pol II) interactions with Mediator. Here, we report that the ability of the Cdk8 module to prevent pol II interactions is independent of the Cdk8-dependent...

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書誌詳細
主要な著者: Elmlund, Hans, Baraznenok, Vera, Lindahl, Martin, Samuelsen, Camilla O., Koeck, Philip J. B., Holmberg, Steen, Hebert, Hans, Gustafsson, Claes M.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2006
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635081/
https://ncbi.nlm.nih.gov/pubmed/17043218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607483103
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