Human DNA polymerase κ forms nonproductive complexes with matched primer termini but not with mismatched primer termini

Human DNA polymerase kappa (pol κ) is a member of the Y family of DNA polymerases that function in translesion synthesis. It synthesizes DNA with moderate fidelity and does not efficiently incorporate nucleotides opposite DNA lesions. Pol κ has the unusual ability to efficiently extend from mismatch...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Carlson, Karissa D., Johnson, Robert E., Prakash, Louise, Prakash, Satya, Washington, M. Todd
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635079/
https://ncbi.nlm.nih.gov/pubmed/17043239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605785103
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